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1

The tale of a tail: The secret behind IGF-1Râs oncogenic power

Crudden, Caitrin, Girnita, Leonard

Journal:

Science Signaling

Year:

2020

File:

PDF, 241 KB

2020

2

Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath

Ron Shapiro, Amit Basu, Henkie Tan, Edward Gray, Akhtar Kahn, Parmjeet Randhawa, Noriko Murase, Adriana Zeevi, Alin Girnita, Diana Metes, Roberta Ness, Debra C. Bass, Anthony J. Demetris, John J. Fung

Journal:

Journal of the American College of Surgeons

Year:

2005

Language:

english

File:

PDF, 311 KB

english, 2005

3

Randomized Controlled Pilot Study of B Cell-Targeted Induction Therapy in HLA Sensitized Kidney Transplant Recipients

Ejaz, N. S., Shields, A. R., Alloway, R. R., Sadaka, B., Girnita, A. L., Mogilishetty, G., Cardi, M., Woodle, E. S.

Journal:

American Journal of Transplantation

Year:

2013

Language:

english

File:

PDF, 823 KB

english, 2013

4

Effect of cytokine and pharmacogenomic genetic polymorphisms in transplantation

Diana M Girnita, Gilbert Burckart, Adriana Zeevi

Journal:

Current Opinion in Immunology

Year:

2008

Language:

english

File:

PDF, 236 KB

english, 2008

5

Anti-HLA alloantibodies in pediatric solid organ transplantation

Alin L. Girnita, Steven A. Webber, Adriana Zeevi

Journal:

Pediatric Transplantation

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

6

Proteasome inhibitor therapy for antibody-mediated rejection

E. S. Woodle, R. C. Walsh, R. R. Alloway, A. Girnita, P. Brailey

Journal:

Pediatric Transplantation

Year:

2011

Language:

english

File:

PDF, 174 KB

english, 2011

7

Clinical significance of the distribution of C4d deposits in different anatomic compartments of the allograft kidney

Batal, Ibrahim, Girnita, Alin, Zeevi, Adriana, Saab, Bassel Abou, Stockhausen, Sean, Shapiro, Ron, Basu, Amit, Tan, Henkie, Morgan, Claire, Randhawa, Parmjeet

Journal:

Modern Pathology

Year:

2008

Language:

english

File:

PDF, 252 KB

english, 2008

8

The significance of renal C4d staining in patients with BK viruria, viremia, and nephropathy

Batal, Ibrahim, Zainah, Hanady, Stockhausen, Sean, Basu, Amit, Tan, Henkie, Shapiro, Ron, Zeevi, Adriana, Girnita, Alin, Randhawa, Parmjeet

Journal:

Modern Pathology

Year:

2009

Language:

english

File:

PDF, 247 KB

english, 2009

9

Role of insulin-like growth factor 1 receptor signalling in cancer

Larsson, O, Girnita, A, Girnita, L

Journal:

British Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 97 KB

english, 2005

10

IMPDH1 Gene Polymorphisms and Association With Acute Rejection in Renal Transplant Patients

Wang, J, Yang, JW, Zeevi, A, Webber, SA, Girnita, DM, Selby, R, Fu, J, Shah, T, Pravica, V, Hutchinson, IV

Journal:

Clinical Pharmacology & Therapeutics

Year:

2007

Language:

english

File:

PDF, 170 KB

english, 2007

11

A link between basic fibroblast growth factor (bFGF) and EWS/FLI-1 in Ewing's sarcoma cells

Girnita, Leonard, Girnita, Ada, Wang, Min, Meis-Kindblom, Jeanne M, Kindblom, Lars-Gunnar, Larsson, Olle

Journal:

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

12

Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene

Xie, Yuntao, Törnkvist, Maria, Aalto, Yan, Nilsson, Gunnar, Girnita, Leonard, Nagy, Bálint, Knuutila, Sakari, Larsson, Olle

Journal:

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

13

The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

Vasilcanu, Daiana, Girnita, Ada, Girnita, Leonard, Vasilcanu, Radu, Axelson, Magnus, Larsson, Olle

Journal:

Year:

2004

Language:

english

File:

PDF, 377 KB

english, 2004

14

The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection

Vasilcanu, D, Weng, W-H, Girnita, A, Lui, W-O, Vasilcanu, R, Axelson, M, Larsson, O, Larsson, C, Girnita, L

Journal:

Year:

2006

Language:

english

File:

PDF, 444 KB

english, 2006

15

Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and β-arrestin1

Girnita, L, Larsson, O, Vasilcanu, R, Vasilcanu, D, Rosengren, L, Natalishvili, N, Sehat, B, Yin, S, Girnita, A, Axelson, M

Journal:

Year:

2007

Language:

english

File:

PDF, 465 KB

english, 2007

16

HLA antibody analysis

Adriana Zeevi, Alin Girnita, Rene Duquesnoy

Journal:

Immunologic Research

Year:

2006

Language:

english

File:

PDF, 268 KB

english, 2006

17

Early outcomes in human lung transplantation with Thymoglobulin or Campath-1H for recipient pretreatment followed by posttransplant tacrolimus near-monotherapy

Kenneth R. McCurry, Aldo Iacono, Adrianna Zeevi, Samuel Yousem, Alin Girnita, Shahid Husain, Diana Zaldonis, Bruce Johnson, Brack G. Hattler, Thomas E. Starzl

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2005

Language:

english

File:

PDF, 216 KB

english, 2005

18

Blocking IGF-1R phosphorylation attenuates intimal hyperplasia through effects on SMC apoptosis, adhesion, migration and proliferation

Joy Roy, Anton Razuvaev, Magnus Axelsson, Leonard Girnita, Olle Larsson, Ulf Hedin

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

19

Aberrant intracellular IGF-1R β-subunit makes receptor knockout cells (IGF1R-/-) susceptible to oncogenic transformation

Natalia Natalishvili, Magnus Axelson, Leonard Girnita, Olle Larsson, Daiana Vasilcanu

Journal:

Experimental Cell Research

Year:

2009

Language:

english

File:

PDF, 986 KB

english, 2009

20

Graft Versus Host Disease in Intestinal Transplantation

George V. Mazariegos, Kareem Abu-Elmagd, Ronald Jaffe, Geoffrey Bond, Rakesh Sindhi, Lillian Martin, Camila Macedo, John Peters, Alin Girnita, Jorge Reyes

Journal:

American Journal of Transplantation

Year:

2004

Language:

english

File:

PDF, 2.07 MB

english, 2004

21

Acute Humoral Rejection of Human Lung Allografts and Elevation of C4d in Bronchoalveolar Lavage Fluid

Geraldine G. Miller, Luis Destarac, Adriana Zeevi, Alin Girnita, Kenneth McCurry, Aldo Iacono, John J. Murray, Deborah Crowe, Joyce E. Johnson, Mathew Ninan, Aaron P. Milstone

Journal:

American Journal of Transplantation

Year:

2004

Language:

english

File:

PDF, 130 KB

english, 2004

22

HLA-Specific Antibodies are Risk Factors for Lymphocytic Bronchiolitis and Chronic Lung Allograft Dysfunction

Alin L. Girnita, Rene Duquesnoy, Samuel A. Yousem, Aldo T. Iacono, Timothy E. Corcoran, Manuela Buzoianu, Bruce Johnson, Kathy J. Spichty, James H. Dauber, Gilbert Burckart, Bartley P. Griffith, Kenne

Journal:

American Journal of Transplantation

Year:

2005

Language:

english

File:

PDF, 167 KB

english, 2005

23

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor

Mario A. Economou, Jiangmei Wu, Daiana Vasilcanu, Linda Rosengren, Charlotta All-Ericsson, Ingeborg Van Der Ploeg, Eline Menu, Leonard Girnita, Magnus Axelson, Olle Larsson, Stefan Seregard, Anders Kv

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2008

Language:

english

File:

PDF, 490 KB

english, 2008

24

The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells

Ada Girnita, Charlotta All-Ericsson, Mario A. Economou, Kristina Åström, Magnus Axelson, Stefan Seregard, Olle Larsson, Leonard Girnita

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2008

Language:

english

File:

PDF, 822 KB

english, 2008

25

Receptors for the liver synthesized growth factors IGF-1 and HGF/SF in uveal melanoma: intercorrelation and prognostic implications

Mario A. Economou, Charlotta All-Ericsson, Vladimir Bykov, Leonard Girnita, Armando Bartolazzi, Olle Larsson, Stefan Seregard

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2008

Language:

english

File:

PDF, 291 KB

english, 2008

26

Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma

Mario A. Economou, Sandra Andersson, Diana Vasilcanu, Charlotta All-Ericsson, Eline Menu, Ada Girnita, Leonard Girnita, Magnus Axelson, Stefan Seregard, Olle Larsson

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2008

Language:

english

File:

PDF, 276 KB

english, 2008

27

Regulatory Role of Mevalonate and N-Linked Glycosylation in Proliferation and Expression of the EWS/FLI-1 Fusion Protein in Ewing's Sarcoma Cells

Min Wang, Yuntao Xie, Leonard Girnita, Gunnar Nilsson, Anica Dricu, Johan Wejde, Olle Larsson

Journal:

Experimental Cell Research

Year:

1999

Language:

english

File:

PDF, 241 KB

english, 1999

28

IGF-1R tyrosine kinase expression and dependency in clones of IGF-1R knockout cells (R−)

Linda Rosengren, Daiana Vasilcanu, Radu Vasilcanu, Sandra Fickenscher, Bita Sehat, Nathalia Natalishvili, Sean Naughton, Shucheng Yin, Ada Girnita, Leonard Girnita, Magnus Axelson, Olle Larsson

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 186 KB

english, 2006

29

Differential roles of SS18–SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth

Maria Törnkvist, Natalia Natalishvili, Yuntao Xie, Ada Girnita, Pádraig D’Arcy, Bertha Brodin, Magnus Axelson, Leonard Girnita

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 866 KB

english, 2008

30

Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs

Hidehito Yoshihara, Toshiaki Fukushima, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Minoru Yoshida, Shun-ichiro Iemura, Tohru Natsume, Tomoichiro Asano, Kazuhiro Chida, Leonard Girnita,

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 471 KB

english, 2012

31

HLA-Specific antibodies are associated with high-grade and persistent-recurrent lung allograft acute rejection

Alin L. Girnita, Kenneth R. McCurry, Aldo T. Iacono, Rene Duquesnoy, Timothy E. Corcoran, Mohamed Awad, Kathy J. Spichty, Samuel A. Yousem, Gilbert Burckart, James H. Dauber, Bartley P. Griffith, Adri

Journal:

The Journal of Heart and Lung Transplantation

Year:

2004

Language:

english

File:

PDF, 87 KB

english, 2004

32

De novo HLA antibodies and lymphocytic bronchiolitis are significantly correlated with bronchiolitis obliterans syndrome in lung transplantation

A.L Girnita, A.T Iacono, T.E Corcoran, S.A Yousem, R Duquesnoy, B Johnson, J.H Dauber, K.J Spichty, B.P Griffith, K.R McCurry, A Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2004

Language:

english

File:

PDF, 67 KB

english, 2004

33

Influence of pre and post-transplant ELISA-detected anti-HLA antibodies on pediatric heart transplant outcome

S Di Filippo, A Girnita, S Tsao, G.J Boyle, S.A Miller, S.A Webber, S.K Gandhi, A Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2004

Language:

english

File:

PDF, 85 KB

english, 2004

34

Impact of pre-transplant T cell depletion combined with tacrolimus monotherapy on the immune responses in lung transplant recipients

A Zeevi, A.L Girnita, K.J Spichty, D Zaldonis, K McDade, A.T Iacono, S.A Yousem, J Britz, R Kowalski, J Woodcock, C Bentlejewski, K.R McCurry

Journal:

The Journal of Heart and Lung Transplantation

Year:

2004

Language:

english

File:

PDF, 74 KB

english, 2004

35

HLA-specific antibodies are associated with lymphocytic bronchiolitis and decreased pulmonary function after lung transplantation

A.L. Girnita, R. Duquesnoy, S.A. Yousem, A.T. Iacono, K.J. Spichty, K.R. McCurry, A. Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2005

Language:

english

File:

PDF, 64 KB

english, 2005

36

Campath preconditioning followed by low maintenance immunosuppression in lung transplant recipients

K.R. McCurry, A.L. Girnita, D.B. Zaldonis, S. Husain, K. Spichty, J. Pilewski, T.E. Starzl, A. Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2005

Language:

english

File:

PDF, 64 KB

english, 2005

37

Measurement of immune function in lung transplant recipients using the Cylex ImmuKnow Assay

A. Zeevi, A. Girnita, K. Spichty, H. Shahid, D. Zaldonis, J. Britz, D. Post, R. Kowalski

Journal:

The Journal of Heart and Lung Transplantation

Year:

2005

Language:

english

File:

PDF, 65 KB

english, 2005

38

Subendothelial C4d deposition and intragraft B cell infiltrates are associated with high-grade acute rejection in lung transplantation

A.L. Girnita, D.N. Ionescu, S.A. Yousem, D. Zaldonis, K.R. McCurry, A. Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2005

Language:

english

File:

PDF, 75 KB

english, 2005

39

Measuring the impact of infection on T cell immunity in lung transplant recipients treated with a T cell depletion protocol

A. Zeevi, A.L. Girnita, K.J. Spichty, H. Shahid, D. Zaldonis, J. Britz, R. Kowalski, J. Woodcock, D. Post, K.R. McCurry

Journal:

The Journal of Heart and Lung Transplantation

Year:

2005

Language:

english

File:

PDF, 78 KB

english, 2005

40

18: Survival in allosensitized children after listing for heart transplantation

B. Feingold, A. Girnita, P. Olesnevich, A. Zeevi, E.S. Quivers, S.A. Miller, S.A. Webber

Journal:

The Journal of Heart and Lung Transplantation

Year:

2006

Language:

english

File:

PDF, 86 KB

english, 2006

41

200: C4d in bronchoalveolar lavage is associated with anti-HLA antibodies in lung transplanted patients

A.L. Girnita, M.T. Lee, W.M. Baldwin, B. Detrick, J.R. Pilewski, S.A. Yousem, K.J. Spichty, K.R. McCurry, A. Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2006

Language:

english

File:

PDF, 85 KB

english, 2006

42

418: Mycophenolate mofetil is associated with decreased de novo anti-HLA alloantibodies in the first year after lung transplantation

A.L. Girnita, A. Zeevi, S.A. Yousem, J. Pilewski, G. Zdanowicz, K.J. Spichty, J. Howe, D. Zaldonis, K.R. McCurry

Journal:

The Journal of Heart and Lung Transplantation

Year:

2007

Language:

english

File:

PDF, 104 KB

english, 2007

43

Survival in Allosensitized Children After Listing for Cardiac Transplantation

Brian Feingold, Pam Bowman, Adriana Zeevi, Alin L. Girnita, Eric S. Quivers, Susan A. Miller, Steven A. Webber

Journal:

The Journal of Heart and Lung Transplantation

Year:

2007

Language:

english

File:

PDF, 406 KB

english, 2007

44

314: Genotypic Variation and Phenotypic Characterization of Granzyme B Gene Polymorphisms

D.M. Girnita, S.A. Webber, R. Ferrell, M.M. Brooks, S. DeCroo, G. Burckart, G. Zdanowicz, R. Chinnock, C. Canter, L. Addonizio, D. Bernstein, J.K. Kirklin, D. Naftel, L. Smith, A.L. Girnita, A. Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2008

Language:

english

File:

PDF, 161 KB

english, 2008

45

333: Impact of Inosine 5’-Monophosphate Dehydrogenase 1,2 and Multidrug Resistance Protein 2 Genetic Polymorphisms on Mycophenolate Mofetil Related Adverse Events in Pediatric Heart Transplant Patients

E.L. Ohmann, G.J. Burckart, Y. Chen, V. Pravica, D.M. Girnita, M.M. Brooks, D.W. Mowrey, A. Zeevi, S.A. Webber

Journal:

The Journal of Heart and Lung Transplantation

Year:

2008

Language:

english

File:

PDF, 64 KB

english, 2008

46

532: Genetic Polymorphisms Impact the Risk of Infection in Pediatric Heart Transplantation – A Multi-Center Study

D.M. Girnita, M.M. Brooks, S.A. Webber, G.J. Burckart, R. Ferrell, A.L. Girnita, R. Chinnock, C. Canter, L. Addonizio, D. Bernstein, J.K. Kirklin, D. Naftel, A. Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2009

Language:

english

File:

PDF, 340 KB

english, 2009

47

200: Clinical Experience with the Use of Virtual Crossmatch in Adult Lung Transplantation

C. Bermudez, A. Girnita, F. Avila, A. Zeevi, M. Crespo, J. Pilewski, G. Speziali, B. Johnson, D. Zaldonis, Y. Toyoda

Journal:

The Journal of Heart and Lung Transplantation

Year:

2009

Language:

english

File:

PDF, 178 KB

english, 2009

48

248: HLA-Specific Antibody Strength and HLA Haplotype Frequency as Predictors for Responsiveness to Desensitization Protocols and Transplantability Rate in Heart Transplant Candidates

A.L. Girnita, C. Bermudez, J.J. Teuteberg, R. Kormos, G. Speziali, Y. Toyoda, T. Sabatine, K. Shoemaker, D. McNamara, L. Jelinek, J. Lomago, A. Zeevi

Journal:

The Journal of Heart and Lung Transplantation

Year:

2009

Language:

english

File:

PDF, 127 KB

english, 2009

49

315: The Impact of HLA-G Polymorphism on Acute Rejection in Pediatric Heart Transplant Recipients

A. Zeevi, M. Brooks, D. Girnita, R. Ferrell, R. Chinnock, C. Canter, L. Addonizio, D. Bernstein, J. Kirklin, D. Naftel, S. Webber

Journal:

The Journal of Heart and Lung Transplantation

Year:

2010

Language:

english

File:

PDF, 103 KB

english, 2010

50

420: The Impact of Repeat HLA Mismatch on Pulmonary Retransplantation

A. Zeevi, D. Zaldonis, K. Spichty, A. Girnita, J. Howe, L. Jelinek, J. Lomago, M. Crespo, J. Pilewski, C. Bermudez, Y. Toyoda

Journal:

The Journal of Heart and Lung Transplantation

Year:

2010

Language:

english

File:

PDF, 97 KB

english, 2010